| Oakamoor | 1 Oakamoor Bed and Breakfast |
| Oakham | 2 Oakham Hotels |
| Oakington | 1 Oakington Bed and Breakfast |
| Oban | 12 Oban Hotels, 20 Bed and Breakfast, 1 Hostel, 7 Vacation Rentals |
| Ogbourne St George | 1 Ogbourne St George Hotel |
| Okehampton | 1 Okehampton Hotel, 2 Bed and Breakfast |
| Old Rayne | 1 Old Rayne Bed and Breakfast |
| Old Romney | 1 Old Romney Hotel |
| Oldmeldrum | 1 Oldmeldrum Hotel |
| Omagh | 1 Omagh Hotel, 1 Hostel |
| Onich | 2 Onich Hotels, 4 Bed and Breakfast, 1 Vacation Rental |
| Opinan | 1 Opinan Bed and Breakfast |
| Orkney | 10 Orkney Hotels, 6 Bed and Breakfast, 4 Vacation Rentals |
| Ormskirk | 1 Ormskirk Hotel, 1 Vacation Rental |
| Orton | 1 Orton Hotel |
| Osmotherley | 1 Osmotherley Bed and Breakfast |
| Oswaldkirk | 1 Oswaldkirk Bed and Breakfast |
| Oswestry | 2 Oswestry Bed and Breakfast |
| Ottershaw | 1 Ottershaw Hotel |
| Ottery St Mary | 2 Ottery St Mary Hotels |
| Ottery St. Mary | 1 Ottery St. Mary Bed and Breakfast |
| Outgate | 1 Outgate Bed and Breakfast |
| Oxenholme | 1 Oxenholme Bed and Breakfast |
| Oxford | 12 Oxford Hotels, 5 Bed and Breakfast, 1 Vacation Rental |
| Oxfordshire | 1 Oxfordshire Hotel |
| Oxhill | 1 Oxhill Bed and Breakfast |
