| Eaglescliffe | 2 Eaglescliffe Hotels |
| Earlish | 1 Earlish Bed and Breakfast |
| Easington | 1 Easington Hotel |
| Easingwold | 2 Easingwold Hotels |
| East Allington | 1 East Allington Bed and Breakfast |
| East Calder | 2 East Calder Bed and Breakfast |
| East Cowes | 2 East Cowes Bed and Breakfast |
| East Dereham | 1 East Dereham Hotel |
| East Grinstead | 1 East Grinstead Bed and Breakfast |
| East Lothian | 1 East Lothian Hotel |
| East Portlemouth | 1 East Portlemouth Vacation Rental |
| East Worldham | 1 East Worldham Bed and Breakfast |
| Eastbourne | 18 Eastbourne Hotels, 7 Bed and Breakfast, 2 Vacation Rentals |
| Eastleigh | 1 Eastleigh Bed and Breakfast |
| Eastling | 1 Eastling Hotel |
| Easton Royal | 1 Easton Royal Bed and Breakfast |
| Eastriggs | 1 Eastriggs Bed and Breakfast |
| Ebberston | 1 Ebberston Bed and Breakfast |
| Edinbane | 2 Edinbane Bed and Breakfast |
| Edinburgh | 58 Edinburgh Hotels, 99 Bed and Breakfast, 11 Hostels, 30 Vacation Rentals |
| Ednam | 1 Ednam Bed and Breakfast |
| Egham | 1 Egham Hotel |
| Egton Bridge | 1 Egton Bridge Hotel |
| Elgin | 3 Elgin Hotels, 1 Bed and Breakfast |
| Elie | 1 Elie Vacation Rental |
| Ellon | 1 Ellon Hotel |
| Elterwater | 1 Elterwater Hotel |
| Ely | 2 Ely Bed and Breakfast |
| Embsay | 1 Embsay Bed and Breakfast |
| Empingham | 1 Empingham Hotel |
| Enfield | 1 Enfield Hotel |
| Ennerdale | 1 Ennerdale Hotel, 1 Bed and Breakfast |
| Enniskillen | 1 Enniskillen Hotel, 1 Vacation Rental |
| Epsom | 1 Epsom Hotel |
| Erskine | 1 Erskine Hotel |
| Escrick | 1 Escrick Bed and Breakfast |
| Eskdale | 3 Eskdale Hotels, 1 Bed and Breakfast, 1 Vacation Rental |
| Ettrickbridge | 1 Ettrickbridge Hotel |
| Evershot | 1 Evershot Bed and Breakfast |
| Evesham | 3 Evesham Hotels |
| Exebridge | 1 Exebridge Bed and Breakfast |
| Exeter | 10 Exeter Hotels, 2 Bed and Breakfast, 1 Hostel, 1 Vacation Rental |
| Exford | 1 Exford Hotel, 2 Bed and Breakfast |
| Exmouth | 2 Exmouth Hotels, 2 Bed and Breakfast, 1 Vacation Rental |
| Eye | 1 Eye Vacation Rental |
